Program Faculty

Activity Chair

Leonard H. Calabrese, DO

Professor of Medicine

Cleveland Clinic Lerner College of Medicine

Director of the R.J. Fasenmyer Center for Clinical Immunology

Cleveland Clinic

Cleveland, OH

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Leonard H. Calabrese, DO, is a graduate of the Kansas City University of Medicine and Biosciences. He performed his internal medicine training at the Cleveland Clinic Foundation followed by a fellowship in rheumatic and immunologic disease. He has been on staff since 1980.

Dr. Calabrese is a professor of medicine at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University and vice chair of the Department of Rheumatic and Immunologic Diseases. He is the director of the RJ Fasenmyer Center for Clinical Immunology at the Cleveland Clinic specializing in diseases of the immune system, in particular, autoimmune and immunodeficiency. He is particularly interested in the immunologic effects of chronic viral infections including HIV and viral hepatitis, which are the subject of both his clinical care and investigation and holds a joint appointment in the Department of Infectious Diseases.

Among his many awards and honors, Dr. Calabrese has received the Phillips Medal of Public Service from the Ohio University College of Osteopathic Medicine, the Bruce Hubbard Stewart Award for humanitarianism, and holds the RJ Fasenmyer Chair of Clinical Immunology at the Cleveland Clinic Foundation.

Dr. Calabrese is also interested in medical history, medical professionalism, and the role of empathy in health care and he holds a joint appointment in the Department of Bioethics, Humanities, and Spiritual Care as well. Dr. Calabrese is a member of numerous societies including the American Osier Society.

Dr. Calabrese has lectured nationally and internationally on the subjects of clinical immunology, rheumatology, and virology and is the author of over 350 published peer reviewed articles, book chapters, and reviews.

Faculty

Joseph E. Craft, MD

Paul B. Beeson Professor of Medicine and Professor of Immunobiology

Chief, Section of Rheumatology

Director, Investigative Medicine

Yale University

Chief of Rheumatology

Yale-New Haven Hospital

New Haven, CT

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Joseph Edgar Craft, MD, is a Paul B. Beeson professor of medicine, chief of the Section of Rheumatology, and professor of immunobiology at the Yale University School of Medicine. He received his undergraduate degree in chemistry from the University of North Carolina at Chapel Hill, and is a graduate of the University of North Carolina School of Medicine. Dr. Craft did postgraduate training in medicine, rheumatology, and immunology at Yale, and has been on the faculty since 1985. At Yale, he teaches graduate and medical students, and directs a research laboratory devoted to understanding CD4 T lymphocyte differentiation and function in normal and autoimmune responses, primarily in systemic lupus erythematosus and inflammatory arthritis. His research has been continually supported by the National Institutes of Health since 1985, where he is an NIH MERIT awardee, and he is the author of over 170 scientific publications.

Dr. Craft is the director of the Investigative Medicine Program at Yale, a unique program designed to provide PhD training for physicians. He is a fellow of the American Association for the Advancement of Science, and a member of the American Society for Clinical Investigation and the Kunkel Society. Dr. Craft also is immediate past chair of the Board of Scientific Counselors at the National Institute of Arthritis, Musculoskeletal, and Skin Diseases (NIAMS), a member of the Board of the Lupus Clinical Trials Consortium, co-chair of the Medical and Scientific Committee of the Connecticut Chapter of the Lupus Foundation of America, and member of the Research Advisory Committee of the Arthritis Foundation. He is a co-founder of L2Diagnostics, a company formed in partnership with Yale University and devoted to the discovery of new diagnostics and therapeutic targets for immunological diseases, and is currently a member of its Board of Directors.

Jonathan Kay, MD

Professor of Medicine

University of Massachusetts Medical School

Director of Clinical Research,

Division of Rheumatology

University of Massachusetts Medical School

Worcester, MA

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Jonathan Kay, MD, received his medical degree from the University of California School of Medicine in San Francisco, CA. He then completed an internship and residency at the hospital of the University of Pennsylvania in Philadelphia, PA and fellowships in rheumatology and immunology at The Brigham and Women’s Hospital and Harvard Medical School in Boston, MA.

Dr. Kay is a professor of medicine at the University of Massachusetts Medical School and a physician at UMass Memorial Medical Center in Worcester, where he directs clinical research in the Division of Rheumatology.

Dr. Kay is a fellow of the American College of Rheumatology and of the American College of Physicians. He is an ad hoc reviewer for many journals and a member of the editorial boards of Arthritis Care & Research, Best Practice and Research Clinical Rheumatology, and the Journal of Clinical Rheumatology. Dr. Kay lectures internationally and is the author of more than 120 publications and book chapters.

Dr. Kay’s clinical interests span the spectrum of rheumatic diseases, with special interest in rheumatoid arthritis, spondyloarthropathies, and other forms of inflammatory arthritis. He was a member of the group that developed the 2010 ACR/EULAR Diagnostic and Classification Criteria for Rheumatoid Arthritis. He chairs the Rheumatology Working Group and is a member of the Internal Medicine and Musculoskeletal Topic Advisory Groups for the World Health Organization in its revision of the International Classification of Diseases (ICD)-11.

Over the past 2 decades, his clinical research has focused on nephrogenic systemic fibrosis (formerly known as nephrogenic fibrosing dermopathy), β2-microglobulin amyloidosis, and other rheumatologic problems of patients with chronic kidney disease. He has been a principal investigator on over 50 clinical trials of novel therapies for rheumatoid arthritis, ankylosing spondylitis, gout, and osteoarthritis. Over the past several years, he has been involved in the development of biosimilars to treat rheumatic diseases.

William F.C. Rigby, MD

Professor of Medicine, Microbiology, and Immunology

Dartmouth Geisel School of Medicine

Hanover, NH

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William F.C. Rigby, MD, is Vice Chairman of Academic Affairs for the Department of Medicine, and Professor of Medicine of Microbiology and Immunology at the Geisel School of Medicine at Dartmouth-Hitchcock Medical Center in Lebanon, NH. He received his medical degree from Harvard Medical School in Boston, MA, and completed his residency and fellowship training at Mary Hitchcock Memorial Hospital in Hanover, NH. His research interests include the scientific underpinnings of the pathogenesis and treatment of rheumatoid arthritis.

Dr. Rigby has been a successful research faculty member of the Geisel Medical School and is active as a molecular/cellular/translational immunologist, clinical researcher, and board-certified rheumatologist. His experience with clinical trials prompted his concentration on biorepository development to identify biomarkers in rheumatoid arthritis and osteoarthritis. This work includes recent publications on Copy Number Variation of Complement C4 genes and CXCL13. The variability of the outcomes of pulmonary disease with defined cystic fibrosis genotypes has made him very interested in the role of the adaptive immune response in shaping clinical phenotypes.

Dr. Rigby has also authored or coauthored articles that have been published in peer-reviewed publications, such as Journal of Immunology, Journal of Rheumatology, Blood, and Arthritis Research and Treatment. He is a member of the American Association of Immunologists, American Association for the Advancement of Science, and American Society for Microbiology.

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