Pediatric EoE: From Diagnosis to Biologic Advancements

1.50CME

1.50CNE

1.50ABP MOC

90MINS

Overview

Provider Statement

This continuing education activity is provided by

Support Statement

This activity is supported by an independent educational grant from Regeneron Pharmaceuticals, Inc. and Sanofi.

Activity Description

Eosinophilic esophagitis (EoE) in pediatric patients presents unique diagnostic and treatment challenges, often leading to delays in care and long-term disease burden. This CE program brings together experts from pediatric gastroenterology to explore the pathophysiology of T2-mediated inflammation, guideline-based diagnostic strategies, and the evolving role of biologics in EoE management. This activity features the dynamic Case Choice format which was presented live, during which attendees selected clinical cases for discussion and provided real-time input on clinical decisions through interactive polling. Faculty reviewed practical approaches to patient selection for biologics, caregiver counseling, and strategies to enhance interprofessional collaboration. The result is actionable insights to improve early recognition, personalize treatment, and enhance long-term outcomes for pediatric patients with EoE.

Target Audience

The intended audience for this activity is US-based physicians, APPs, and nurses who specialize in gastroenterology or pediatric gastroenterology involved in the management of patients with EoE.

Learning Objectives

Upon successful completion of this activity, participants should be better able to:

Incorporate knowledge of T2-mediated inflammation into treatment planning for pediatric patients with EoE.
Implement guideline-based diagnostic strategies to differentiate EoE from other esophageal disorders in pediatric patients.
Integrate biologic therapy into the management of pediatric patients with EoE based on the latest clinical evidence and guideline recommendations.
Apply collaborative care strategies and interprofessional approaches across pediatric providers to support long-term disease management in pediatric patients with EoE.

Activity Chair

Mirna Chehade, MD, MPH, AGAF, FAAAAI
Professor of Pediatrics and Medicine
Founding Director, Mount Sinai Center for Eosinophilic Disorders
Icahn School of Medicine at Mount Sinai
New York, NY

Faculty

Amanda B. Muir, MD
Associate Professor of Pediatrics
Division of Gastroenterology
Children's Hospital of Philadelphia
Philadelphia, PA

Vincent A. Mukkada, MD
Professor of Pediatrics, University of Cincinnati College of Medicine
Medical Director of Gastroenterology, Hepatology, and Nutrition
Cincinnati Center for Eosinophilic Disorders
Interdisciplinary Feeding Team
Cincinnati Children's Hospital Medical Center
Cincinnati, OH

Sophia A. Patel, MD
Assistant Professor
Cleveland Clinic Lerner College of Medicine/Case Western Reserve University School of Medicine
Pediatric Gastroenterology, Hepatology, and Nutrition
Cleveland Clinic Children's
Cleveland, OH

Planners/Reviewers

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
Linda A. Giarraputo, BS, PA-C
Barbara A. Niedz, PhD, RN, CPHQ

Accreditation

ACCME Jointly accredited In support of improving patient care, Vindico Medical Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Credit Designation

Vindico Medical Education designates this enduring material for a maximum of 1.50 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

abp moc Successful completion of this CME activity, which includes participation in the evaluation component, enables the learner to earn up to 1.50 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit learner completion information to ACCME for the purpose of granting ABP MOC credit.

Upon successful completion, learners who opt-in by providing their ABP ID and DOB (MM/DD) will earn MOC points equivalent to the amount of CME credits claimed for the activity.

Vindico Medical Education designates this activity for 1.50 nursing contact hours. Nurses should claim only the credit commensurate with the extent of their participation in the activity.

aapa Vindico Medical Education has been authorized by the American Academy of Physician Associates (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.50 AAPA Category 1 CME credits. Approval is valid until December 18, 2026. PAs should only claim credit commensurate with the extent of their participation.

Nurse practitioners can apply for AMA PRA Category 1 Credit(s)™ through the American Academy of Nurse Practitioners Certification Board (AANPCB). AANPCB will accept AMA PRA Category 1 Credit(s)™ from organizations accredited by ACCME.

This enduring material is approved for 1 year from the date of original release, December 19, 2025, to December 18, 2026.

How to Participate in This Activity and Obtain CE Credit

To participate in this activity, you must read the objectives, answer the polling and pretest questions, view the content, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 2 of the 3 posttest questions correctly. If a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ certificate, Contact Hour(s) certificate, or AAPA Category 1 CME credit certificate.

In addition to providing a downloadable certificate, CME Providers accredited by the Accreditation Council for Continuing Medical Education (ACCME) have the ability to transmit CME credit data for all US physicians to an online repository, the ACCME Program and Activity Reporting System (PARS). CME credit data submitted to PARS can be viewed, managed, and tracked by US physicians in "CME Passport," a free, centralized web application. US Physicians who opt-in by providing their medical license number, state of licensure, and date of birth will have their credits automatically reported to the ACCME.

Disclosures

Vindico Medical Education adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Individuals in a position to control the content of a continuing education activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Relationship information is accurate at the time of content development.

Activity Chair and Faculty report the following relevant financial relationship(s)

Mirna Chehade, MD, MPH, AGAF, FAAAAI
Consultant: Adare/Ellodi, Allakos, Apogee, AstraZeneca, Phathom, Recludix, Regeneron, Sanofi, Shire/Takeda, Uniquity Bio
Independent Research Contractor: Adare/Ellodi, Allakos, AstraZeneca, Regeneron, Shire/Takeda

Amanda B. Muir, MD
Consultant: EsoCap, Regeneron, Takeda

Vincent A. Mukkada, MD
Consultant: Phathom, Regeneron, Sanofi, Takeda

Sophia A. Patel, MD
Advisor: Sanofi Regeneron
Consultant: Sanofi Regeneron

Planners/Reviewers report the following relevant financial relationship(s)

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
No relevant financial relationships to disclose.

Linda A. Giarraputo, BS, PA-C
No relevant financial relationships to disclose.

Barbara A. Niedz, PhD, RN, CPHQ
No relevant financial relationships to disclose.

Vindico Medical Education staff report the following relevant financial relationship(s)

No relevant financial relationships to disclose.

Signed disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

Unlabeled and Investigational Usage

The audience is advised that this continuing education activity may contain references to unlabeled uses of FDA-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non–FDA-approved or investigational use of products/devices.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2025 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any Vindico Medical Education continuing education activity does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the FDA. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

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