Available IBEC Curriculum

  • Rheumatic Immune-related Adverse Events
  • LECTUREIBECCME
  • Rheumatic Immune-related Adverse Events: Multidisciplinary Perspectives on Recognition and Management

  • The introduction of immune checkpoint inhibitors has had a great impact on the field of oncology. However, these new therapies are associated with a spectrum of autoimmune and systemic inflammatory reactions known as immune-related adverse events (irAEs). Rheumatologists are likely to encounter a wide variety of irAEs as the use of immune checkpoint inhibitors expands in the treatment of several cancers. Thus, it is critical for rheumatologists to be aware of these complications to accurately diagnose and manage the toxicities of immune checkpoint inhibitors in collaboration with treating oncologists. In this CME activity, expert faculty will review the role of the immune system in tumor biology and the appropriate management of irAEs associated with immune checkpoint inhibitors. Case-based examples will illustrate best practices for recognizing and managing these adverse events...More »

  • Giant Cell Arteritis
  • LECTUREIBECCME
  • Giant Cell Arteritis: Overcoming the Limitations of Conventional Agents with Biologic Therapy

  • Giant cell arteritis (GCA) is the most common form of medium- and large-vessel vasculitis. If left untreated, patients with GCA are at increased risk for a range of short- and long-term complications. Diagnosis of GCA remains difficult due to the non-specific nature of many early symptoms. Until recently, therapeutic options were limited to prolonged, high-dose glucocorticoid therapy, which has the potential for many undesirable side effects. In this CME activity, expert faculty will discuss the clinical and immunopathologic features of GCA, current therapeutic options, as well as data for new and emerging agents. Case-based discussion will provide practical strategies for overcoming the diagnostic and treatment challenges of GCA.....More »

  • Best of RA Forum
  • LECTUREIBECCME
  • Best of RA Forum® 2017: The Role of the Immune System in Disease Pathology and Treatment

  • Rheumatoid arthritis (RA) is a progressive and painful systemic inflammatory disease that preferentially attacks the synovium of the joints, leading to joint destruction, debility, and deformity. Increased understanding of the underlying pathophysiology of RA has made a remarkable difference in its treatment and prognosis. Numerous therapeutic agents with diverse targets and mechanisms have been added to the RA armamentarium, allowing for intervention at various stages in the pathogenic process of the disease. By understanding the underlying immunologic mechanisms driving RA progression, clinicians involved in the management of patients with RA will be better equipped to evaluate the clinical and pharmacologic safety, as well as the efficacy profiles of current and emerging therapies. In this RA Forum®, leading rheumatologists will integrate discussions of basic immunologic principles with current and emerging RA treatments and interactive cases, as well as discuss treatment guidelines and use of biosimilars in the clinic....More »

  • Clinical Advances in RA and PsA/SpA
  • ARTICLEIBECCME
  • Advances in the Immunopathogenesis of Rheumatic Diseases: Lessons from Checkpoint Immunotherapy of Cancer

  • Rheumatoid arthritis (RA) is a progressive and painful systemic inflammatory disease that preferentially attacks the synovium of the joints, leading to joint destruction, debility, and deformity. Increased understanding of the underlying pathophysiology of RA has made a remarkable difference in its treatment and prognosis. Numerous therapeutic agents with diverse targets and mechanisms have been added to the RA armamentarium, allowing for intervention at various stages in the pathogenic process of the disease. By understanding the underlying immunologic mechanisms driving RA progression, clinicians involved in the management of patients with RA will be better equipped to evaluate the clinical and pharmacologic safety, as well as the efficacy profiles of current and emerging therapies. This activity will review advances in the immunopathogenesis of rheumatic diseases and lessons from checkpoint immunotherapy of cancer....More »

  • Clinical Advances in RA and PsA/SpA
  • ARTICLEIBECCME
  • Treatment Guidelines for RA 2017: Implementation and Controversies for Efficacy and Safety

  • Rheumatoid arthritis (RA) is a progressive and painful systemic inflammatory disease that preferentially attacks the synovium of the joints, leading to joint destruction, debility, and deformity. Increased understanding of the underlying pathophysiology of RA has made a remarkable difference in its treatment and prognosis. Numerous therapeutic agents with diverse targets and mechanisms have been added to the RA armamentarium, allowing for intervention at various stages in the pathogenic process of the disease. This activity will review treatment guidelines for RA in 2017....More »

  • Clinical Advances in RA and PsA/SpA
  • ARTICLEIBECCME
  • Clinical Advances in Rheumatoid Arthritis and Psoriatic Arthritis/Spondyloarthropathy: Emerging Therapies

  • Rheumatoid arthritis (RA) is a progressive and painful systemic inflammatory disease that preferentially attacks the synovium of the joints, leading to joint destruction, debility, and deformity. Increased understanding of the underlying pathophysiology of RA has made a remarkable difference in its treatment and prognosis. Numerous therapeutic agents with diverse targets and mechanisms have been added to the RA armamentarium, allowing for intervention at various stages in the pathogenic process of the disease. This activity will review clinical advances in RA as well as psoriatic arthritis (PsA) and spondyloarthropathy (SpA)....More »

  • Best of AWIR Immunology
  • LECTUREIBECCME
  • Best of AWIR Immunology Bootcamp

  • Immune-mediated inflammatory disease (IMID) is a group of clinically heterogenous disorders that share common immunopathology. The continued evaluation and refinement of biologic therapies in the treatment of IMID have provided significant benefit to patients suffering from these disorders. However, recognizing the underlying immunopathological mechanisms of IMID is essential for understanding how current and emerging biologics exert their effects. In this CME educational activity, held during the Association of Women in Rheumatology National Conference, experts in the field will review and discuss the immunological pathways that regulate the activity of the immune system in IMID...More »

  • Immunosenescence, Inflammaging, and Mindfulness
  • CLINICAL CASEIBECCME
  • Improving the Psoriatic Disease Continuum

  • Psoriasis is a chronic inflammatory disease affecting more than 3% of the general population. Among patients with psoriasis, 5% to 30% are affected by psoriatic arthritis (PsA). Patients with psoriasis and comorbid PsA experience significant disease burden, including reduced quality of life, decreased physical function, and increased comorbidities. Despite recent advances in understanding the pathophysiology and improved treatment options, psoriasis and PsA remain underdiagnosed and undertreated. To improve outcomes for patients with psoriasis and PsA, it is important for physicians to understand the domains of disease activity, associated comorbidities, and available treatment options. This case-based activity utilizes a question-and-answer format to review the clinical evidence as well as guideline recommendations for the diagnosis and treatment of psoriasis and PsA...More »

  • Immunosenescence, Inflammaging, and Mindfulness
  • CLINICAL CASEIBECCME
  • Missed Opportunities in Managing Patients with Psoriatic Disease

  • Psoriasis is a chronic inflammatory disease affecting more than 3% of the general population. Among patients with psoriasis, 5% to 30% are affected by psoriatic arthritis (PsA). Patients with psoriasis and comorbid PsA experience significant disease burden, including reduced quality of life, decreased physical function, and increased comorbidities. Despite recent advances in understanding the pathophysiology and improved treatment options, psoriasis and PsA remain underdiagnosed and undertreated. To improve outcomes for patients with psoriasis and PsA, it is important for physicians to understand the domains of disease activity, associated comorbidities, and available treatment options. This case-based activity utilizes a question-and-answer format to review the clinical evidence as well as guideline recommendations for the diagnosis and treatment of psoriasis and PsA...More »

  • Rheumatoid Arthritis and Allied Conditions
  • EXPERT VIDEOIBECCME
  • Rheumatoid Arthritis and Allied Conditions

  • Drs. Calabrese and Tessesr examine the immunopathogenesis and therapeutic landscape of RA and allied conditions as well as strategies to mitigate risk from biologic and immune-based agents...More »

  • Rare and Serious Adverse Events
  • EXPERT VIDEOIBECCME
  • Rare and Serious Adverse Events

  • In this Curbside Consult, Leonard H. Calabrese, DO and Elizabeth Kirchner, MSN, CNP examine the immunopathogenesis and therapeutic landscape of RA and allied conditions as well as strategies to...More »

  • Treatment with Small Molecules
  • EXPERT VIDEOIBECCME
  • Treatment with Small Molecules

  • Drs. Calabrese and Gibofsky examine the immunopathogenesis and therapeutic landscape of RA and allied conditions as well as strategies to mitigate risk from biologic and immune-based agents...More »

  • Combining Biologics and Small Molecules?
  • EXPERT VIDEOIBECCME
  • Combining Biologics and Small Molecules?

  • Drs. Calabrese and Tesser examine the immunopathogenesis and therapeutic landscape of RA and allied conditions as well as strategies to mitigate risk from biologic and immune-based agents...More »

  • Treatment Discontinuation
  • EXPERT VIDEOIBECCME
  • Treatment Discontinuation

  • Drs. Calabrese and Gibofsky examine the immunopathogenesis and therapeutic landscape of RA and allied conditions as well as strategies to mitigate risk from biologic and immune-based agents...More »

  • Best of RA Forum™ 2016
  • LECTUREIBECCME
  • Best of RA Forum™ 2016

  • Rheumatoid arthritis (RA) is a progressive and painful systemic inflammatory disease that preferentially attacks the synovium of the joint leading to joint destruction, debility, and deformity...More »

  • RA Patient with a History of Malignancy
  • EXPERT VIDEOIBECCME
  • RA Patient with a History of Malignancy

  • Drs. Tesser and Kay examine the immunopathogenesis and therapeutic landscape of RA and allied conditions as well as strategies to mitigate risk from biologic and immune-based agents....More »

  • Loss of Response
  • EXPERT VIDEOIBECCME
  • Loss of Response

  • In this series of Curbside Consults, experts in RA will present cases from their own practices and have a collegial discussion about the challenges introduced by the cases, with a focus on key concepts in immunology as they relate to clinical care...More »

  • Treating TNF Non-responders
  • EXPERT VIDEOIBECCME
  • Treating TNF Non-responders

  • In this series of Curbside Consults, experts in RA will present cases from their own practices and have a collegial discussion about the challenges introduced by the cases, with a focus on key concepts in immunology as they relate to clinical care....More »

  • Window of Opportunity
  • EXPERT VIDEOIBECCME
  • Vaccinations for RA Patients

  • In this Curbside Consult, Leonard H. Calabrese, DO and Elizabeth Kirchner, MSN, CNP examine the immunopathogenesis and therapeutic landscape of RA and allied conditions as well as strategies to mitigate risk from biologic and immune-based agents...More »

  • Window of Opportunity
  • EXPERT VIDEOIBECCME
  • Window of Opportunity

  • In this Curbside Consult, Leonard Calabrese, DO and Allan Gibofsky, MD, JD, MACR, FACP, FCLM examine the immunopathogenesis and therapeutic landscape of RA and allied conditions as well as strategies to mitigate risk from biologic and immune-based agents...More »

  • Pre-Rheumatoid Arthritis
  • EXPERT VIDEOIBECCME
  • Pre-Rheumatoid Arthritis

  • In this Curbside Consult, Jonathan Kay, MD and Allan Gibofsky, MD, JD, MACR, FACP, FCLM examine the immunopathogenesis and therapeutic landscape of RA and allied conditions as well as strategies to mitigate risk from biologic and immune-based agents...More »

  • Treatment Escalation in a Newly Diagnosed Patient
  • EXPERT VIDEOIBECCME
  • Treatment Escalation in a Newly Diagnosed Patient

  • In this Curbside Consult, Leonard H. Calabrese, DO and Elizabeth Kirchner, MSN, CNP describe the underlying principles of innate and adaptive immunity as they contribute to understanding the mechanism of action of existing and developing immune-based therapies...More »

  • Pathogenesis of Rheumatoid Arthritis 2016
  • Pathogenesis of Rheumatoid Arthritis 2016

  • This highly interactive infographic activity will walk you through the latest advancements in the immunologic mechanisms involved in the pathogenesis and treatment of rheumatoid arthritis. You will be able to see and interact with phases of pre-RA, body modifications that occur in established RA, and get an overview of currently available treatment options...More »

  • Th17 Cells in Health and Disease
  • ARTICLEIBECCME
  • Th17 Cells in Health and Disease

  • IL-17 is slowly being recognized as having an important role in the development and persistence of certain autoimmune and rheumatic diseases. This activity will discuss the discovery timeline for the… More »

  • Regulatory T Cells in Autoimmunity
  • LECTUREIBECCME
  • Regulatory T Cells in Autoimmunity

  • A cascade of immunologic events contributes to the development of autoimmunity and diseases such as rheumatoid arthritis. This lecture will review the different types of T regulatory cells, their… More »

  • Complement in Rheumatic Disease
  • LECTUREIBECCME
  • Complement in Rheumatic Disease

  • The immune system has many complex components. In this activity, learners will review the role complement plays in host protection and, conversely, how its disruption may contribute to the… More »

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